In a large skillet or Dutch oven, cook the ground beef over medium heat until no longer pink. Drain grease and return skillet to stovetop. Add the ketchup, mustard, onion powder, garlic powder, seasoned salt, salt and pepper to the skillet. Stir until combined. Add the macaroni, beef broth and water. Bring to a boil, then reduce to a simmer over medium-low heat. Simmer for 10-12 minutes, or until pasta is soft and liquids have thickened.